Is it Possible to Get Pregnant with Low AMH?

Trying to conceive can be an emotional journey for many couples, especially when faced with potential fertility issues. One such concern is having a low Anti-Mullerian Hormone (AMH) level. In this blog, we’ll explore the implications of low AMH levels for women in their 20s, 30s, and 40s, and discuss the available options for those trying to conceive.

• Understanding AMH

Anti-Müllerian Hormone (AMH) is a hormone produced by primordial follicles within the ovaries. It serves as an indicator of ovarian reserve and provides an approximate number of follicles present. Measuring AMH levels, alongside assessing the antral follicle count using ultrasound, helps determine the ovarian reserve.

Normal AMH values range between 2 to 4 or 4.5. Levels higher than this may indicate Polycystic Ovary Syndrome (PCOS), while values below 1.5 suggest low ovarian reserve. Levels below 1 are considered very low, and levels below 0.5 are a cause for serious concern.

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• What is AMH?

AMH, or Anti-Mullerian Hormone, is a hormone produced by the cells surrounding a woman’s developing eggs in her ovaries. It serves as an indicator of a woman’s ovarian reserve, which refers to the number of quality eggs remaining in her ovaries. A higher AMH level generally indicates a larger number of good-quality eggs, while a lower AMH level suggests fewer eggs and possibly reduced fertility.

• Conceiving with Low AMH in your 20s and Early 30s:

  For women aged 20 to 25, the chances of getting pregnant naturally are generally high, even with low AMH levels. At this age, routine fertility checkups may not be necessary, and the woman might conceive without knowing her AMH level is low. In this case, low AMH simply indicates a reduced ovarian reserve, but it does not mean that a woman cannot conceive naturally.

  If a woman in her 20s or early 30s is diagnosed with low AMH, it’s important to try aggressively to conceive. However, if natural conception proves difficult, consulting a fertility specialist is recommended.

  For women under 35 with low AMH, undergoing In-Vitro Fertilization (IVF) as soon as possible may increase the chances of a successful pregnancy. If Assisted Reproductive Technologies (ARTs) like Intrauterine Insemination (IUI) are attempted without success, shifting to IVF while the patient is still young can improve the odds.

  Women in the Poseidon classification, which categorizes patients based on ovarian reserve and other factors, tend to have better responses to fertility treatments. This is because AMH levels naturally decline with age, making it increasingly important to conceive at a younger age when possible.

• Conceiving with Low AMH at 35 and Above:

For women with low AMH levels aged 35 and above, conceiving can be a challenging task. Chromosomal abnormalities in embryos, which can affect the development of healthy blastocysts, become more common as a woman ages. For women under 35 with low AMH, the rate of chromosomal abnormalities is less than 40%. However, this rate increases to 50% for women above 35 and reaches over 85% for those above 40. As a result, the number of viable eggs decreases, and the chances of a successful pregnancy are reduced.

Oocytes and ovarian reserves can be thought of as a box of sweets: they cannot be preserved indefinitely and will naturally deplete over time. AMH levels typically decrease by 10 to 15% regularly. If a woman has low AMH levels at an early age, it’s crucial to try aggressively to conceive and consult an expert if unsuccessful.

For women above 35 with low AMH, it’s essential to consider IVF as soon as possible and consult a fertility specialist for more information.

Wrapping up

In summary, the ability to conceive with low AMH levels varies based on a woman’s age. For younger women, natural conception may still be possible, while older women may need to consider fertility treatments like IVF.

The bottom line is to plan and act early when faced with low AMH levels. For those who are young and wish to delay pregnancy, freezing eggs can be a viable option to preserve fertility for later use.

This process, known as oocyte cryopreservation, involves extracting, freezing, and storing a woman’s eggs for potential future use. This can be particularly beneficial for women with low AMH who want to ensure they have a better chance of conceiving at a later stage in life.

In conclusion, while low AMH levels can pose challenges for women trying to conceive, it is essential to understand that it is not an insurmountable obstacle. By acting proactively, seeking the guidance of fertility specialists, and considering fertility treatments when necessary, many women with low AMH can still achieve their dream of becoming mothers. Remember, early planning and intervention are key to increasing the chances of a successful pregnancy.